If not already active, be sure to damage yourself upon the Curse Room door before accepting Soul or Black Hearts to activate the Whore of Babylon state. Without any health upgrades, they will lower Eve's health into her Whore of Babylon state, and can potentially hold useful items and/or Soul/Black Hearts to protect Eve after transforming. Curse Rooms are generally useful rooms to find at the beginning of a run.Eve works well when she's low on health using Devil Beggars and Blood Donation Machines are good ways to activate Whore of Babylon. This allows Eve to get to her Whore of Babylon while also granting the damage-up of the Razor Blade, and without lowering the Devil deal chance. Upon donating 439 coins to the Greed Donation Machine, Eve will start with the Razor Blade.However, the use of Pyromaniac does count. When unlocking Eve, gaining Red Heart containers or using Yum Heart does not count as picking up heart pickups. Eve has a 16.25% chance instead of the usual 10% for any nonspecific Heart drop to turn into a Soul Heart.Additionally, Eve's 0.75x damage multiplier will change to 1.00x as long as Whore of Babylon is active.
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